Bilateral Scleritis and Retinal Vasculitis in Microscopic Polyangiitis

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Key words: vasculitis, ANCA, granulomatosis with polyangiitis, microscopic polyangiitis, Birmingham Vasculitis Activity Score, Vasculitis Damage Index, cyclophosphamide, rituximab

NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom. Raashid Luqmani, DM, FRCP, Professor Please address correspondence to: Prof. Raashid Luqmani, NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, Unive...

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Central nervous system vasculitis in pediatric microscopic polyangiitis.

Microscopic polyangiitis is a small vessel vasculitis, associated with myeloperoxidaseantineutrophil cytoplasmic antibody. It rarely occurs in children. Central nervous system involvement in pediatric microscopic polyangiitis is not a well known entity with perhaps only five cases till date. We hereby present a 14-year-old girl with arthralgia, seizure, leukocytoclastic vasculitis, interstit...

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Microscopic polyangiitis: a rare ANCA-associated small-vessel vasculitis.

Microscopic Polyangiitis (MPA) is an autoimmune disease characterized by pauci-immune, necrotizing, small-vessel vasculitis without clinical or pathological evidence of necrotizing granulomatous inflammation. Because many different organ systems may be involved, a wide range of symptoms are possible in MPA. Cutaneous involvement is not frequent. We describe a young girl who presented with multi...

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Microscopic polyangiitis.

Microscopic polyangiitis is a systemic vasculitis affecting smal-l and medium-sized vessels and is characteristically associated with a focal and segmental necrotizing glomerulonephritis. It may present as a pulmonary-renal syndrome with rapidly progressive glomerulonephritis and alveolar hemorrhage, but the pattern of disease will vary according to the organ systems involved. Granulomatous dis...

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necrotizing scleritis in granulomatosis with polyangiitis

purpose: to report two cases of granulomatosis with polyangiitis (gpa) presented ocular manifestations. cases report: we report two cases of scleritis with red eye, one of them was a 30 years old female patient with saddle nose and positive c-anca and the other one was a 56 year-old female patient with lung cavitation and positive c-anca. both cases undergone corticosteroid and immunosuppressiv...

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ژورنال

عنوان ژورنال: Ophthalmology

سال: 2016

ISSN: 0161-6420

DOI: 10.1016/j.ophtha.2016.06.050